Various Factors that causes Metabolic Disorders
Various Factors that causes Metabolic Disorders Metabolic disorders affect individuals due to various factors, and their root causes can be multifaceted. Let’s delve into the reasons: Genetics : Inherited Mutations : Genetic variations can lead to dysfunctional enzymes or proteins involved in metabolism. Examples : Phenylketonuria (PKU), Gaucher’s disease, and lysosomal storage disorders result from specific gene mutations. Enzyme Deficiencies : Enzymes : These catalysts drive biochemical reactions. Deficiencies : Lack of specific enzymes disrupts metabolic pathways. Example : Lactose intolerance due to insufficient lactase enzyme. Organ Dysfunction : Pancreas : Insufficient insulin production causes diabetes. Liver : Impaired liver function affects nutrient processing. Thyroid : Thyroid disorders alter metabolism. Mitochondrial Dysfunction : Mitochondria : Energy-producing organelles. Mutations or Damage : Impact energy production. Result : Disorders like mitochondrial myopathy. ...